PSYCHOLOGICAL COMPONENT OF CHRONIC PAIN: CLINICAL SIGNIFICANCE AND REHABILITATION OPPORTUNITIES
DOI:
https://doi.org/10.32782/3041-2005/2026-2.8Keywords:
chronic pain, psychological factors, pain catastrophizing, fear of movement, biopsychosocial model, cognitive behavioral therapy, rehabilitation, self-managementAbstract
Chronic pain is regarded as a complex, multifactorial phenomenon that represents a significant medical and socioeconomic challenge for modern healthcare systems. According to current estimates, more than 20 % of the adult population worldwide experience various forms of chronic pain, leading to a reduced quality of life, decreased functional capacity, and an increased risk of disability. This paper summarizes contemporary scientific approaches to understanding the role of psychological factors in the development and persistence of chronic pain syndrome. The aim of the study was to analyze the influence of psychoemotional and cognitive-behavioral factors on the course of chronic pain and to determine their relevance for rehabilitation strategies. The study is based on the analysis of recent scientific publications indexed in international databases such as PubMed, Scopus, and Web of Science, including systematic reviews, meta-analyses, and clinical studies published over the past decade. Methods of analysis, systematization and synthesis were applied. The findings indicate that psychological factors, including depression, anxiety, pain catastrophizing, and fear of movement, play a crucial role in pain chronicity, influencing pain intensity, functional impairment and treatment outcomes. Maladaptive cognitive-behavioral patterns and impaired emotional regulation contribute to the persistence of chronic pain. Particular attention is paid to the fear-avoidance model and pain catastrophizing as key mechanisms underlying pain chronicity. Current evidence supports the use of a biopsychosocial approach to rehabilitation integrating medical, psychological and physical interventions. Cognitive-behavioral therapy, mindfulness-based interventions and selfmanagement programs have demonstrated effectiveness in reducing pain intensity and improving patients’ quality of life. Multidisciplinary rehabilitation programs appear to be the most effective strategy, as they target multiple mechanisms involved in chronic pain. Consideration of psychological factors is essential for effective management and rehabilitation of patients with chronic pain. The integration of psychological interventions into clinical practice contributes to improved functional outcomes and enhanced quality of life.
References
Mills S., Nicolson K., Smith B. Chronic pain: a review of its epidemiology. British Journal of Anaesthesia. 2019. Vol. 123.
№ 2. P. e273–e283. DOI: https://doi.org/10.1016/j.bja.2019.03.023
Miller R. M., Kaiser R. S. Psychological Characteristics of Chronic Pain: a Review of Current Evidence and Assessment Tools
to Enhance Treatment. Current pain and headache reports. 2018. Vol. 22. № 3. Р. 22. DOI: https://doi.org/10.1007/s11916-018-0663-y
Turk D., Wilson H., Cahana A. Treatment of chronic non-cancer pain. The Lancet. 2011. Vol. 377. № 9784. P. 2226–2235.
DOI: https://doi.org/10.1016/S0140-6736(11)60402-9
Gatchel R., McGeary D. Interdisciplinary chronic pain management. American Psychologist. 2014. Vol. 69. № 2. P. 119–130.
DOI: https://doi.org/10.1037/a0035514
Cohen S., Vase L., Hooten W. Chronic pain: an update. The Lancet. 2021. Vol. 397. No. 10289. P. 2082–2097.
DOI: https://doi.org/10.1016/S0140-6736(21)00393-7
Jensen M. P., Turk D. C. Contributions of psychology to pain research and treatment. American Psychologist. 2014. Vol. 69.
№ 2. P. 105–118. DOI: https://doi.org/10.1037/a0035641
Kerns R. D., Sellinger J., Goodin B. R. Psychological treatment of chronic pain. Annual Review of Clinical Psychology. 2011.
Vol. 7. P. 411–434. DOI: https://doi.org/10.1146/annurev-clinpsy-090310-120430
Karos K. et al. Fear of pain changes movement: motor behavior following the acquisition of pain-related fear. European
Journal of Pain. 2017. Vol. 21. № 5. DOI: https://doi.org/10.1002/ejp.1044
Linton S. J., Shaw W. S. Impact of psychological factors in the experience of pain. Physical Therapy. 2011. Vol. 91. № 5.
P. 700–711. DOI: https://doi.org/10.2522/ptj.20100330
Yang S., Chang M. C. Chronic pain: structural and functional changes in brain structures and associated negative affective
states. International Journal of Molecular Sciences. 2019. Vol. 20. № 13. P. 3130. DOI: https://doi.org/10.3390/ijms20133130
Apkarian A. V., Hashmi J. A., Baliki M. N. Pain and the brain: specificity and plasticity of the brain in clinical chronic pain.
Pain. 2011. Vol. 152. Suppl. 3. P. S49–S64. DOI: https://doi.org/10.1016/j.pain.2010.11.010
Sullivan M. J. L., Tripp D. A. Pain catastrophizing: controversies, misconceptions and future directions. The Journal of Pain. 2024. Vol. 25. № 3. P. 575–587. DOI: https://doi.org/10.1016/j.jpain.2023.07.004
Vlaeyen J. W. S., Crombez G., Linton S. J. The fear-avoidance model of pain. Pain. 2016. Vol. 157. № 8. P. 1588–1589. DOI: https://doi.org/10.1097/j.pain.0000000000000574
Pare C., Sullivan M. J. L. Pain catastrophizing and fear of movement: detection and intervention. Clinical Pain Management. 2022. DOI: https://doi.org/10.1002/9781119701170.ch27
Vlaeyen J. W. S., Crombez G. Behavioral approaches to chronic pain. Annual Review of Clinical Psychology. 2020. Vol. 16. P. 187–212. DOI: https://doi.org/10.1146/annurev-clinpsy-050718-095744
Lumley M. A. Emotional awareness and expression therapy for chronic pain. Current Rheumatology Reports. 2019. Vol. 21.
№ 7. P. 30. DOI: https://doi.org/10.1007/s11926-019-0829-6
Kucyi A., Davis K. D. The dynamic pain connectome. Trends in Neurosciences. 2015. Vol. 38, Issue 2. Р. 86–95. DOI: https://doi.org/10.1016/j.tins.2014.11.006
Curatolo M. Central sensitization and pain: pathophysiologic and clinical insights. Current Neuropharmacology. 2024. Vol. 22. № 1. P. 15–22. DOI: https://doi.org/10.2174/1570159X20666221012112725
Eccleston C., Fisher E., Craig L. et al. Psychological therapies for the management of chronic pain in adults. Cochrane Database of Systematic Reviews. 2015. № 10. CD011259. DOI: https://doi.org/10.1002/14651858.CD011259.pub2
Ehde D. M., Dillworth T. M., Turner J. A. Cognitive-behavioral therapy for individuals with chronic pain: Efficacy, innovations, and directions for research. American Psychologist. 2014. Vol. 69, № 2. P. 153–166. DOI: https://doi.org/10.1037/a0035747
Hadley G., Novitch M. B. CBT and CFT for chronic pain. Current Pain and Headache Reports. 2021. Vol. 25, № 5. P. 35. DOI: https://doi.org/10.1007/s11916-021-00948-1
Cherkin D. C., Sherman K. J., Turner J. A. Mindfulness-based stress reduction vs cognitive behavioral therapy for chronic low back pain. Journal of the American Medical Association. 2016. Vol. 316. № 6. P. 663–664. DOI: https://doi.org/10.1001/jama.2016.7951
Staudt M. D. The multidisciplinary team in pain management. Neurosurgery Clinics of North America. 2022. Vol. 33. № 3. P. 241–249. DOI: https://doi.org/10.1016/j.nec. 2022.02.002
Kamper S. J., Apeldoorn A. T., Chiarotto A. et al. Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: Cochrane systematic review and meta-analysis. BMJ. 2015. Vol. 350. P. h444. DOI: https://doi.org/10.1136/bmj.h444
Vase L., Wager T. D., Eccleston C. Opportunities for chronic pain self-management. The Lancet. 2025. Vol. 405. № 10491. P. 1781–1790. DOI: https://doi.org/10.1016/S0140-6736(25)00404-0
Moreno-Ligero M., Moral-Munoz J. A., Salazar A., Failde I. mHealth intervention for improving pain, quality of life,
and functional disability in patients with chronic pain. JMIR mHealth and uHealth. 2023. Vol. 11. e40844. DOI: https://doi.org/10.2196/40844
Hu X.-Y., Young B., Santer M. et al. Self-management interventions for chronic widespread pain including fibromyalgia. Pain. 2025. Vol. 166. № 3. P. e36–e50. DOI: https://doi.org/10.1097/j.pain.0000000000003379
Goldsmith R., Rudd S., Harding S. Self-management interventions for adults with chronic lumbar radicular pain. Musculoskeletal Science and Practice. 2025. Vol. 78. P. 103364. DOI: https://doi.org/10.1016/j.msksp.2025.103364
Okoli G. N., Lam O. L. T., Reddy V. K. Self-management programs for chronic non-cancer pain. The Canadian Journal of Neurological Sciences. 2023. Vol. 50. № 4. P. 584–596. DOI: https://doi.org/10.1017/cjn.2022.261



